Crispr

China’s CRISPR twins might have had their brains inadvertently enhanced

Pre-Existing Immunity to CRISPR Found in 96% of People in Study

Cancer cells engineered with CRISPR slay their own kin

Using gene editing, scientists have hoodwinked tumor cells into turning against their own kind. Cancer cells circulating in the bloodstream have something of a homing instinct, able to find and return to the tumor where they originated. To capitalize on that ability, researchers engineered these roving tumor cells to secrete a protein that triggers a death switch in resident tumor cells they encounter.

Using CRISPR to edit coral

The work was published online in the Proceedings of the National Academy of Sciences. Phillip Cleves, PhD, a postdoctoral scholar at Stanford and coral enthusiast, is first author on the study. Cleves and his collaborators were able to use CRISPR to successfully introduce mutations to three genes (red fluorescent protein, green fluorescent protein and fibroblast growth factor 1a, a gene that is thought to help regulate new coral colonization) in a specific type of coral, Acropora millepora, definitively showing for the first time that the gene-editing technology could be successful in coral species.

Biology Will Be the Next Great Computing Platform

Crispr, the powerful gene-editing tool, is revolutionizing the speed and scope with which scientists can modify the DNA of organisms, including human cells. So many people want to use it—from academic researchers to agtech companies to biopharma firms—that new companies are popping up to staunch the demand. Companies like Synthego, which is using a combination of software engineering and hardware automation to become the Amazon of genome engineering.

CRISPR’d Food, Coming Soon To A Supermarket Near You

For years now, the US Department of Agriculture has been flirting with the latest and greatest DNA manipulation technologies. Since 2016, it has given free passes to at least a dozen gene-edited crops, ruling that they fall outside its regulatory purview. But on Wednesday, March 28, the agency made its relationship status official; effective immediately, certain gene-edited plants can be designed, cultivated, and sold free from regulation.

It’s Time to Make Human-Chimp Hybrids

It is a bit of a stretch, but by no means impossible or even unlikely that a hybrid or a chimera combining a human being and a chimpanzee could be produced in a laboratory. After all, human and chimp (or bonobo) share, by most estimates, roughly 99 percent of their nuclear DNA. Granted this 1 percent difference presumably involves some key alleles, the newgene-editing tool CRISPR offers the prospect (for some, the nightmare) of adding and deleting targeted genes as desired.