Scientists develop 10-minute universal cancer test
Scientists have developed a universal cancer test that can detect traces of the disease in a patient’s bloodstream. The cheap and simple test uses a colour-changing fluid to reveal the presence of malignant cells anywhere in the body and provides results in less than 10 minutes. While the test is still in development, it draws on a radical new approach to cancer detection that could make routine screening for the disease a simple procedure for doctors.
Read MoreDual-action cancer-killing virus developed by Oxford scientists
Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells that are tricked into shielding the cancer from the immune syste The virus targets carcinomas, which are the most common type of cancer and start in cells in the skin or tissues that line or cover internal organs. A microscope image of a human colorectal adenocarcinoma showing the fibroblasts (brown) surrounding the cancer cells (blue), protecting them from the immune system (PA/Medical Research Council).
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Alphabet unit halts glucose-detecting contact lens project
Alphabet Inc’s life sciences division Verily said on Friday that it was putting on hold one of its oldest and highest-profile projects, a smart contact lens designed to help monitor sugar levels. The project, started in 2014, aimed to help diabetics better manage their blood sugar levels by embedding sensors on a contact lens to monitor the glucose levels in their tears. In a blog update, Verily cited here insufficient consistency in the correlation between tear glucose and blood glucose concentrations to support the requirements of a medical device.
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A cure for cancer: how to kill a killer
Last month, the Nobel prize in medicine was awarded for two breakthrough scientific discoveries heralded as having “revolutionised cancer treatment”, and “fundamentally changed the way we view how cancer can be managed”. One of them went to a charismatic, harmonica-playing Texan named Jim Allison for his breakthrough advances in cancer immunotherapy. His discovery had resulted in transformative outcomes for cancer patients and a radical new direction for cancer research.
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‘Spectacular’ diabetes treatment could end daily insulin injections
A potential medical breakthrough that could put an end to the daily insulin injections endured by people living with diabetes has been unveiled by Dutch scientists. By destroying the mucous membrane in the small intestine and causing a new one to develop, scientists stabilised the blood sugar levels of people with type 2 diabetes. The results have been described as “spectacular” – albeit unexpected – by the chief researchers involved.
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Researchers Identify Molecule With Anti-Aging Effects On Vascular System
A molecule produced during fasting or calorie restriction has anti-aging effects on the vascular system, which could reduce the occurrence and severity of human diseases related to blood vessels, such as cardiovascular disease, according to a study led by Georgia State University. In this study, the research team explores the link between calorie restriction (eating less or fasting) and delaying aging, which is unknown and has been poorly studied. The findings are published in the journal Molecular Cell.
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UBC breakthrough opens door to $100 ultrasound machine
Engineers at the University of British Columbia have developed a new ultrasound transducer, or probe, that could dramatically lower the cost of ultrasound scanners to as little as $100. Their patent-pending innovation—no bigger than a Band-Aid—is portable, wearable and can be powered by a smartphone. Conventional ultrasound scanners use piezoelectric crystals to create images of the inside of the body and send them to a computer to create sonograms.
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‘Ground-breaking’ diabetes insulin drug trialled in Cardiff
A ‘ground-breaking’ drug that helps people with diabetes re-grow insulin-making cells has been developed. About 19,000 people live with Type 1 of the condition in Wales and 90% have less than 5% of these cells left. This means they have to inject insulin
Read MoreAI System Approved For Diabetic Retinopathy Diagnosis
A system designed by a University of Iowa ophthalmologist that uses artificial intelligence (AI) to detect diabetic retinopathy without a person interpreting the results earned Food and Drug Administration (FDA) authorization in April, following a clinical trial in primary care offices. Results of that study were published Aug. 28 online in Nature Digital Medicine, offering the first look at data that led to FDA clearance for IDx-DR, the first medical device that uses AI for the autonomous detection of diabetic retinopathy. The clinical trial, which also was the first study to prospectively assess the safety of an autonomous AI system in patient care, compared the performance of IDx-DR to the gold standard diagnostic for diabetic retinopathy, which is the leading cause of vision loss in adults and one of the most severe complications for the 30.3 million Americans living with diabetes.
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New anti-cancer drugs put cancers to sleep—permanently
In a world first, Melbourne scientists have discovered a new type of anti-cancer drug that can put cancer cells into a permanent sleep, without the harmful side-effects caused by conventional cancer therapies. Published today in the journal Nature, the research reveals the first class of anti-cancer drugs that work by putting the cancer cell to sleep – arresting tumour growth and spread without damaging the cells’ DNA. The new class of drugs could provide an exciting alternative for people with cancer, and has already shown great promise in halting cancer progression in models of blood and liver cancers, as well as in delaying cancer relapse.
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New anti-cancer drugs put cancers to sleep—permanently
In a world first, Melbourne scientists have discovered a new type of anti-cancer drug that can put cancer cells into a permanent sleep, without the harmful side-effects caused by conventional cancer therapies. Published today in the journal Nature, the research reveals the first class of anti-cancer drugs that work by putting the cancer cell to sleep – arresting tumour growth and spread without damaging the cells’ DNA. The new class of drugs could provide an exciting alternative for people with cancer, and has already shown great promise in halting cancer progression in models of blood and liver cancers, as well as in delaying cancer relapse.
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EPA is allowing asbestos back into manufacturing
On June 1, the EPA authorized a “SNUR” (Significant New Use Rule) which allows new products containing asbestos to be created on a case-by-case basis. The U.S. Environmental Protection Agency has enacted a SNUR (Significant New Rule) allowing companies to use new asbestos-containing products on a case-by-case basis. (Courtesy Mesothelioma + Asbestos Awareness Center)
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The inconvenient truth about cancer and mobile phones
On 28 March this year, the scientific peer review of a landmark United States government study concluded that there is “clear evidence” that radiation from mobile phones causes cancer, specifically, a heart tissue cancer in rats that is too rare to be explained as random occurrence. Eleven independent scientists spent three days at Research Triangle Park, North Carolina, discussing the study, which was done by the National Toxicology Program of the US Department of Health and Human Services and ranks among the largest conducted of the health effects of mobile phone radiation. NTP scientists had exposed thousands of rats and mice (whose biological similarities to humans make them useful indicators of human health risks) to doses of radiation equivalent to an average mobile user’s lifetime exposure.
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First ever color X-ray on a human
New Zealand scientists have performed the first-ever 3-D, colour X-ray on a human, using a technique that promises to improve the field of medical diagnostics, said Europe’s CERN physics lab which contributed imaging technology. The new device, based on the traditional black-and-white X-ray, incorporates The CERN technology, dubbed Medipix, works like a camera detecting and counting individual sub-atomic particles as they collide with pixels while its shutter is open.
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Cancer cells engineered with CRISPR slay their own kin
Using gene editing, scientists have hoodwinked tumor cells into turning against their own kind. Cancer cells circulating in the bloodstream have something of a homing instinct, able to find and return to the tumor where they originated. To capitalize on that ability, researchers engineered these roving tumor cells to secrete a protein that triggers a death switch in resident tumor cells they encounter.
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Our cancer preventing genes revealed
In our bodies, we all have genes working hard to prevent cancer. If they don’t do their job properly, rogue cells can mutate and develop into the life-threatening disease. The malfunction of one so-called “super tumour suppressor gene” known as p53 causes at least half of all cancers.
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Human blood cells transformed into functional neurons
Human immune cells in blood can be converted directly into functional neurons in the laboratory in about three weeks with the addition of just four proteins, researchers at the Stanford University School of Medicine have found. The conversion occurs with relatively high efficiency — generating as many as 50,000 neurons from 1 milliliter of blood — and it can be achieved with fresh or previously frozen and stored blood samples, which vastly enhances opportunities for the study of neurological disorders such as schizophrenia and autism. A paper describing the findings was published online June 4 in the Proceedings of the National Academy of Sciences.
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Drone Delivery Becomes a Reality in Remote Pacific Islands
Currently, health workers in Vanuatu often hike over mountains to deliver vaccines–but drones can fly over them. This September, delivery drones will begin to fly the friendly skies of Vanuatu. And this isn’t a one-shot demonstration, like many of the stunts we’ve seen from the likes of Amazon and Google.
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China overtakes U.S. for healthy lifespan: WHO data
GENEVA (Reuters) – China has overtaken the United States in healthy life expectancy at birth for the first time, according to World Health Organization data. Chinese newborns can look forward to 68.7 years of healthy life ahead of them, compared with 68.5 years for American babies, the data – which relates to 2016 – showed. American newborns can still expect to live longer overall – 78.5 years compared to China’s 76.4 – but the last 10 years of American lives are not expected to be healthy.
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Ingestible “bacteria on a chip” could help diagnose disease
This “bacteria-on-a-chip” approach combines sensors made from living cells with ultra-low-power electronics that convert the bacterial response into a wireless signal that can be read by a smartphone. In the new study, appearing in the May 24 online edition of Science, the researchers created sensors that respond to heme, a component of blood, and showed that they work in pigs. They also designed sensors that can respond to a molecule that is a marker of inflammation.
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How gut microbes are joining the fight against cancer
Cancer has been a late bloomer in the microbiome revolution that has surged through biomedicine. Over the past few decades, scientists have linked the gut’s composition of microbes to dozens of seemingly unrelated conditions — from depression to obesity. Cancer has some provocative connections as well: inflammation is a contributing factor to some tumours and a few types of cancer have infectious origins.
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Leading UK scientist reveals likely cause of childhood leukaemia
Professor Mel Greaves from The Institute of Cancer Research, London, assessed the most comprehensive body of evidence ever collected on acute lymphoblastic leukaemia (ALL) – the most common type of childhood cancer. His research concludes that the disease is caused through a two-step process of genetic mutation and exposure to infection that means it may be preventable with treatments to stimulate or ‘prime’ the immune system in infancy. The first step involves a genetic mutation that occurs before birth in the foetus and predisposes children to leukaemia – but only 1 per cent of children born with this genetic change go on to develop the disease.
Read MoreMice with 3D-Printed Ovaries Successfully Give Birth
AsKatherine Kornei at Science reports,the researchers used a 3D printer to build the scaffolding of the organs, weaving layers of gelatin to createtiny (15 x 15 millimeter) ovaries on glass slides. They then tested the scaffolds by embedding a follicle—the tiny sacs composed of hormone-secreting cells that containthe maturing eggs. This test suggested that the tightest weave supported the highest survival rates, reports Kornei.
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How an AI Startup Could Defeat Now Unbeatable Bugs
The need for new medications is higher than ever, but so is the cost and time to bring them to market. Developing a new drug can cost billions and take as long as 14 years, according to the U.S. Food and Drug Administration. Yet with all that effort, only 8 percent of drugs make it to market, the FDA said.
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The spectacular power of Big Lens
If you have been wearing glasses for years, like me, it can be surprising to discover that you perceive the world thanks to a few giant companies that you have never heard of. Worrying about the fraying edge of motorway lights at night, or words that slide on the page, and occasionally spending a fortune at the opticians is, for many of us, enough to think about. And spectacles are unusual things.
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The Microbiome is the Fundamental Future of Personalized Medicine
If anything makes us human it’s our minds, thoughts and emotions. And yet a controversial new concept is emerging that claims gut bacteria are an invisible hand altering our brains. Science is piecing together how the trillions of microbes that live on and in all of us—our microbiome—affect our physical health.
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